Hull Fundamentals Futures Option Markets Solution

list here the most popular supplements for acne

1nadtlenek benzoyl (benzacne, brevoxyl)
2 salicylic acid (various ointments and creams such as Cream Garnier clean skin)

Antibiotics are used topically to treat acne for many years in various forms. Due to the antibacterial activity, local antibiotic therapy is particularly indicated in case of pustular acne, maculopapular. A limitation of antibiotic therapy is a relatively frequent occurrence of bacterial resistance and very rare - an allergic reaction. The relatively frequent giving erythromycin resistance, hence it is preferable to combine benzoyl peroxide with erythromycin. Tetracycline often have resistance, but less than erythromycin and clindamycin. Among the topical antibiotics include:
clindamycin (Dalacin T 1% in liquid, emulsion, gel, Cleocin T 1% solution, lotion, gel) 2.5% erythromycin
cyclic carbonate of erythromycin (Davercin, liquid), 2% erythromycin (Aknemycin, ointment and liquid, A / T / S 2% gel, 2% Erygel gel Emgel 2% gel, 2% solution EryDerm, Ermax 2% solution, Theramycin with a 2% solution, Erycette 2% solution at 60 wacikach or handkerchiefs, T -Stat 2% solution at 60 wacikach or handkerchiefs),
tetracycline,
preparations, such as Aknemycin Plus (4% erythromycin and tretinoin 0.025%), Zineryt (erythromycin + zinc acetate) Benzamycin (erythromycin 30 mg and 50 mg benzoyl peroxide / g).
Azelaic acid is available in the form of 20% cream called Skinoren (Azelex in the U.S.) is often used in local therapy of acne. It is characterized by multi-mechanism of action: in addition to antimicrobial activity directed against the strains of Propionibacterium acnes and Staphylococcus epidermidis, showed activity and keratolytic przeciwzaskórnikową. With the inhibition of melanogenesis is used in removing stains postinfection. Its effectiveness is comparable with other preparations for topical application, is considered a second line drug. The advantage is rarer incidence of adverse events and lack of development of drug resistance in bacterial strains tested.

Retinoids are increasingly being used in local therapy of acne. It should be mentioned the following products: tretinoin acid (vitamin A acid, all-trans vitamin A), isotretinoin (13-cis acid, vitamin A) and the recently introduced adapalen and tazaroten. The action of retinoids is the exfoliation process standardization within sebaceous glands ducts, allowing the evacuation of mucus glands and as a result of significant reductions in komedogenezy. Hence, the main indication do ich stosowania jest acne comedonica. Objawy niepożądane pod postacią wysuszenia, złuszczania, zaczerwienienia skóry są najczęstsze w przypadku stosowania tretynoiny (Atrederm, Airol, Retin A). Ze względu na możliwość wystąpienia odczynu zapalnego zaleca się stosowanie tych preparatów wieczorem. Aby zminimalizować objawy niepożądane, należy rozpoczynać terapię od niższych stężeń i aplikacji leku co 2, 3 dni, stopniowo przechodząc do częstszego stosowania. Zaleca się przed aplikacją leku umyć twarz przy użyciu łagodnego mydła i odczekać 20-30 minut aż do całkowitego wyschnięcia skóry. This action significantly reduces the irritating effects of retinoids.

drug with similar mechanism of action and effectiveness is isotretinoin (13-cis acid, vitamin A), the advantage (particularly in the form of a cream) is a smaller number of side effects. A new form of tretinoin is the preparation of Retin-A Micro, available as a 0.1% gel, which is a combination of tretinoin in microspheres, which occupy a selective switches. Thanks to them, tretinoin is slowly released, resulting in a better tolerated. Besides, unlike other forms of isotretinoin, this formulation does not phototoxic reactions, and microspheres absorb the extra layer of fat from the skin. New form of tretinoin is Avita, produced in the form of a cream 0.025% and 0.025% gel. This medicine contains polyolprepolymer-2, which prevents the violent and excessive drug penetration, thus reducing side effects.

newly introduced drugs and tazaroten adapalen, available through 0.1% gels, are considered very safe. They are also the only retinoid with a significant anti-inflammatory activity. Adapalen has a special affinity for the hair follicle, probably due to the microcrystalline structure. Due to the effect of keratolytic and anti-inflammatory is used both in comedonica acne, as well as in inflammatory acne. It is especially recommended for patients with dry skin or associated with atopic dermatitis. Tazaroten, available in the form of 0.05 and 0.1% of non-alcoholic gels, is applicable not only in the mild and intermediate forms of acne, but also some forms of psoriasis. Efficacy is greater in higher concentrations, which, unfortunately, also causes more comparable to tretinoin, skin irritation. Unlike the latter, however, does not cause hypersensitivity reactions to sunlight. Similarly tretinoin formulations, tazaroten is absolutely contraindicated in pregnant women.

general treatment of acne include antibiotics, hormonal therapy, vitamin A derivatives, rarely kortykosteroidoterapię, non-steroidal anti-inflammatory drugs, vaccines, and occasionally autoszczepionki.